Spatial Localization of Recent Ancestors for Admixed Individuals
نویسندگان
چکیده
منابع مشابه
Spatial Localization of Recent Ancestors for Admixed Individuals
Ancestry analysis from genetic data plays a critical role in studies of human disease and evolution. Recent work has introduced explicit models for the geographic distribution of genetic variation and has shown that such explicit models yield superior accuracy in ancestry inference over nonmodel-based methods. Here we extend such work to introduce a method that models admixture between ancestor...
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Inference of ancestry from genetic data is a fundamental problem in computational genetics, with wide applications in human genetics and population genetics. The treatment of ancestry as a continuum instead of a categorical trait has been recently advocated in the literature. Particularly, it was shown that a European individual’s geographic coordinates of origin can be determined up to a few h...
متن کاملDiscussion: Recent Common Ancestors of All Present-day Individuals
It is a pleasure to be able to comment on such an interesting and insightful paper. Demographic properties of population genetics models have been of interest for more than 50 years, and suddenly we have a sharp new perspective on properties of a diploid Wright–Fisher model. The results in Chang’s paper are all the more interesting for their contrast with the analogue for haploid (that is, sing...
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The notion of our common ancestors has received considerable attention of late in both the scientific and lay communities. Principally this attention has focused on ‘Mitochondrial Eve,’ defined to be the woman who lies at the confluence of our maternal ancestry lines, and who is believed to have lived 100,000–200,000 years ago. More recent attention has been given to our common paternal ancesto...
متن کاملRecent Common Ancestors of All Present-day Individuals
Previous study of the time to a common ancestor of all present-day individuals has focused on models in which each individual has just one parent in the previous generation. For example, “mitochondrial Eve” is the most recent common ancestor (MRCA) when ancestry is defined only through maternal lines. In the standard Wright-Fisher model with population size n, the expected number of generations...
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ژورنال
عنوان ژورنال: G3 Genes|Genomes|Genetics
سال: 2014
ISSN: 2160-1836
DOI: 10.1534/g3.114.014274